CENTER FOR NEUROLOGIC STUDY
7590 FAY AVENUE 517, LA JOLLA, CA 92037

Total Revenue
$1,690,290
Total Expenses
$971,183
Net Assets
$25,215,689

Organizations Filed Purposes: THE CENTER FOR NEUROLOGIC STUDY HAS A STRAIGHTFORWARD MISSION:ADVANCE THE CAUSE OF PATIENTS WITH DISORDERS OF THE NERVOUS SYSTEM. THIS HAS BEEN ACCOMPLISHED THROUGH PROVIDING PATIENT AND FAMILY SUPPORT, DRUG DEVELOPMENT AND CLINICAL RESEARCH.

THE CENTER FOR NEUROLOGIC STUDY HAS, SINCE ITS INCEPTION OVER 40 YEARS AGO, FOCUSED ON THE BETTERMENT OF PERSONS WITH PRESENTLY INCURABLE NEURODEGENERATIVE DISEASES. AT OUR OUTSET THIS WAS A DAUNTING CHALLENGE AND STILL IS. TO INVEST IN THE FUTURE, THE CENTER IS FUNDING START UP COMPANIES WHO ARE DEVELOPING NOVEL THERAPEUTICS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS AND WE ARE SUPPORTING STUDENTS WHO ARE INTERESTED IN CONDUCTING LABORATORY RESEARCH BEFORE GOING TO MEDICAL SCHOOL OR ENROLLING IN A PHD PROGRAM. FURTHER, CNS CONTINUES ITS HIGHLY SUCCESSFUL PROGRAM OF DRUG DISCOVERY AND DEVELOPMENT (FOR DETAILS VISIT CNSONLINE.ORG).

RESEARCH: WORK UNDERTAKEN AT CNS PLAYED A ROLE IN THE INTRODUCTION OF INTERFERON FOR THE TREATMENT OF MULTIPLE SCLEROSIS. THE CENTER PARTICIPATED IN NUMEROUS NATIONAL, EXPERIMENTAL TREATMENT TRIALS INVOLVING AMYOTROPHIC LATERAL SCLEROSIS, ALZHEIMER'S DISEASE, NEUROPATHY WHICH LED TO THE DISCOVERY OF NUEDEXTA WHICH HAS BEEN APPROVED FOR USE IN THE UNITED STATES AND EUROPE. REMARKABLY, THE DRUG HAS IMPROVED FUNCTION IN BOTH ALZHEIMER'S DISEASE AND ALS PATIENTS, WITH STUDY RESULTS PUBLISHED IN MAJOR SCIENTIFIC JOURNAlS. PIONEERING WORK DONE AT CNS IN COLLABORATION WITH THE UNIVERSITY OF CALIFORNIA AND IONIS PHARMACEUTICALS IS WIDELY BELIVED TO BE THE MOST PROMISING STRATEGY FOR TREATING NEURODEGENERATIVE DISEASES SUCH AS HUNTINGTON'S DISEASE AND FAMILIAL AMYOTROPHIC LATERAL SCLEROSIS. THIS STRATEGY INVOLVES THE SYNTHESIS OF SMALL MOLECULES THAT DOWN REGULATE THE EXPRESSION OF MUTANT PROTEINS IN THE BRAIN. THE LATTER RESULTS WERE PRESENTED AT THE 2018 ANNUAL MEETING OF THE AMERICAN ACADEMY OF NEUROLOGY.

PUBLIC EDUCATION: RESEARCH CONDUCTED AT CNS HAS BEEN PRESENTED PUBLICALLY AT MEDICAL AND SCIENTIFIC MEETINGS AND PUBLISHED IN LEADING SCIENTIFIC JOURNALS. THESE ACTIVITIES HAVE BEEN REPORTED UPON IN LOCAL AND NATIONAL MEDIA, INCLUDING NBC AND CNN TELEVISION, THE SAN DIEGO UNION TRIBUNE, THE LOS ANGELES AND NEW YORK TIMES AND SCIENTIFIC AMERICAN. CNS ALSO PROVIDES INFORMATION ABOUT NEUROLOGICAL DISEASES TO PATIENTS, PHYSICIANS AND THE GENERAL PUBLIC VIA IT'S WEBSITE (CNSONLINE.ORG). ADDITIONALY CNS IS INVOLVED IN ORGANIZING AN ANNUAL CONFERENCE ON AMYOTROPHIC LATERAL SCLEROSIS IN COLLABORATION WITH ACADEMIC INSTITUTUIONS IN CALIFORNIA (CALIFORNIA ALS SUMMIT).

Executives Listed on Filing

Total Salary includes financial earnings, benefits, and all related organization earnings listed on tax filing

NameTitleHours Per WeekTotal Salary
Richard A Smith MdPresident25$212,500
Kathleen MyersSECRETARY/TREAS8$48,000
Randall Kaye MdDirector0.3$0
Daryl SmithDirector0.5$0
David Louis Cutchin PhdDirector0.5$0
Steve BordnerDirector0.3$0

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