VITAL STRATEGIES INC
100 BROADWAY 4TH FL, NEW YORK, NY 10005 www.vitalstrategies.org

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Organizations Filed Purposes: AT VITAL STRATEGIES' CORE IS A VISION OF A WORLD WHERE EVERYONE IS PROTECTED BY A STRONG PUBLIC HEALTH SYSTEM.

WE ENVISION A WORLD WHERE EVERY PERSON IS PROTECTED BY A STRONG PUBLIC HEALTH SYSTEM. WE BELIEVE PASSIONATELY THAT PROGRESS CAN BE MADE AGAINST EVEN THE MOST DIFFICULT HEALTH CHALLENGES BY PARTNERING LOCAL COMMITMENT AND GLOBAL EXPERTISE. WE IMPLEMENT PROGRAMS THAT STRENGTHEN THESE PARTNERS AND THE HEALTH SYSTEMS THEY SUPPORT WORKING TO IMPROVE THE LIVES OF BILLIONS.

RESOLVE - MORE INVESTMENT AND TECHNICAL SUPPORT IS NEEDED TO REDUCE THE BURDEN OF CARDIOVASCULAR DISEASE (CVD) AND RELATED, PREVENTABLE DEATHS. SIMILARLY, INVESTMENT AND TECHNICAL ASSISTANCE CAN IMPROVE THE CAPACITY OF COUNTRIES TO PREVENT, IDENTIFY, AND RESPOND EFFECTIVELY TO INFECTIOUS DISEASE OUTBREAKS AND PREVENT THEM FROM BECOMING EPIDEMICS.RESOLVE TO SAVE LIVES WILL ACCELERATE AND SCALE UP THE IMPLEMENTATION OF PROVEN TOOLS AND STRATEGIES TO IDENTIFY AND CLOSE DEADLY GAPS IN PUBLIC HEALTH AND SAVE MILLIONS OF LIVES. A TEAM OF GLOBAL HEALTH EXPERTS WILL WORK WITH GOVERNMENTS AND CIVIL SOCIETY IN LOW- AND MIDDLE-INCOME COUNTRIES TO SUPPORT THE ADOPTION OF EVIDENCE-BASED STRATEGIES THAT WILL DELIVER LIFE-SAVING CHANGES IN HEALTH POLICIES AND SYSTEMS. THE INITIATIVE WILL ALSO STRENGTHEN TRACKING AND ACCOUNTABILITY SYSTEMS TO GUIDE AND ACCELERATE PROGRESS. RESOLVE TO SAVE LIVES WILL WORK WITH AND SUPPORT KEY PARTNERS INCLUDING THE WORLD HEALTH ORGANIZATION, THE CDC FOUNDATION, WORLD BANK, CAMPAIGN FOR TOBACCO-FREE KIDS, AND THE JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH.THE FIVE-YEAR, $225 MILLION RESOLVE TO SAVE LIVES INITIATIVE IS FUNDED BY BLOOMBERG PHILANTHROPIES, THE BILL & MELINDA GATES FOUNDATION, AND GATES PHILANTHROPY PARTNERS, WHICH IS FUNDED WITH SUPPORT FROM THE CHAN ZUCKERBERG FOUNDATION. IT IS LED BY DR. TOM FRIEDEN, FORMER DIRECTOR OF THE US CENTERS FOR DISEASE CONTROL AND PREVENTION, AND HOUSED AT VITAL STRATEGIES, WHICH WORKS IN 60 COUNTRIES WITH THE VISION OF A WORLD WHERE EVERY PERSON IS PROTECTED BY A STRONG PUBLIC HEALTH SYSTEM.

TOBACCO CONTROL:IN 2019, VITAL STRATEGIES' WORK STRENGTHENED PROTECTIONS FOR HUNDREDS OF MILLIONS OF PEOPLE AGAINST THE HARMS OF TOBACCO, FROM NEW SMOKE-FREE LAWS PASSED IN SOME OF CHINA'S LARGEST CITIES, TO A TOTAL E-CIGARETTE BAN IN INDIA. THIS YEAR WE ALSO RAN OUR FIRST GOVERNMENT-FUNDED ANTI-INDUSTRY CAMPAIGN IN TURKEY WORTH MORE THAN USD $30 MILLION DOLLARS. IN ALL OF OUR PRIORITY COUNTRIES, THE TOBACCO INDUSTRY WAS MET, AND OFTEN PUSHED BACK, WITH A FIGHT.OUR GAINS WERE ACHIEVED BY SUPPORTING 41 INTEGRATED, ROBUST MEDIA CAMPAIGNS IN 11 PRIORITY COUNTRIES THAT HELPED ACHIEVE 19 NATIONAL AND SUBNATIONAL MPOWER AND ANTI-INDUSTRY POLICY WINS. OUR CAMPAIGNS REACHED OVER 746 MILLION PEOPLE IN 2019. EACH CAMPAIGN WAS CRAFTED FOR MAXIMUM IMPACT USING SOCIAL SCIENCE RESEARCH, INNOVATIVE DIGITAL STRATEGY, AND CARRIED OUT BY STAFF ON THE GROUND WITH DEEP IN-COUNTRY KNOWLEDGE AND A FOCUS ON BI PARTNER POLICY PRIORITIES.WHILE THE NUMBER OF POLICY WINS IS IMPRESSIVE, ANOTHER PIECE OF THIS STORY OF PROGRESS IS HOW THEY WERE ACHIEVED. IN 2019, GOVERNMENTS CONTRIBUTED MORE THAN US $60 MILLION IN FINANCIAL OR IN-KIND INVESTMENT TO RUN MEDIA CAMPAIGNS THAT HELPED TO SUPPORT CESSATION, REDUCE INITIATION, CHANGE BEHAVIOR AND SECURE MPOWER POLICIES. IN SEVEN PRIORITY COUNTRIES, MEDIA CAMPAIGNS WERE ON AIR OR ONLINE FOR THE MAJORITY OF THE YEAR, KEEPING TOBACCO CONTROL MESSAGES FRONT AND CENTER FOR BILLIONS OF PEOPLE. NATIONAL GOVERNMENTS SOUGHT OUT OUR HELP TO STRENGTHEN NATIONAL TOBACCO CONTROL LAWS AND MEET FIVE AND 10-YEAR GOALS IN CHINA, INDIA, BANGLADESH, MEXICO AND UKRAINE, AMONG OTHERS. CAMPAIGNS IN BANGLADESH, PAKISTAN, INDIA AND TURKEY BENEFITED FROM REGULATIONS THAT PROVIDE FREE AIRTIME FOR PUBLIC SERVICE MESSAGES, WHICH WE HELPED ENSURE WERE UTILIZED. THIS STEP TOWARD SUSTAINABILITY DEMONSTRATES GOVERNMENT BUY-IN AND OWNERSHIP, A TREMENDOUS ADVANCE FROM WHEN WE BEGAN THIS WORK A DECADE AGO.WE ALSO RAN 41 SOCIAL MEDIA CAMPAIGNS ACROSS SEVEN COUNTRIES THAT FOUGHT FOR THOSE POLICIES BI PARTNERS ARE CONCENTRATED ON, SUPPORTED ENFORCEMENT, CESSATION, BUILT ANTI E-CIGARETTE SENTIMENT, AND DREW OUR SUPPORTERS TO OFFLINE EVENTS. OUR ENERGIZED BASE OF SOCIAL MEDIA SUPPORTERS GREW FROM 890,000 LAST YEAR TO 1.9 MILLION TODAY. THESE 1.9 MILLION PEOPLE FOLLOW OUR TOBACCO CONTROL SOCIAL MEDIA MESSAGES ON FACEBOOK AND INSTAGRAM IN BANGLADESH, INDIA, INDONESIA, MEXICO AND THE PHILIPPINES. SOCIAL MEDIA HAS BECOME A KEY CHANNEL TO REACH AND ACTIVATE OUR AUDIENCE THROUGH A MIX OF ORGANIC AND PROMOTED CONTENT. WE ALSO CONTINUE TO USE SOCIAL MEDIA VIDEO PROMOTIONS TO FURTHER THE REACH OF OUR TOBACCO CONTROL MASS MEDIA CAMPAIGNS. OUR WORK - PRESS LAUNCHES, EVENTS AND OTHER ACTIVITIES ALSO RESULTED IN 1,100 MEDIA STORIES ACROSS PRIORITY COUNTRIES THAT BOLSTERED THE REACH OF OUR CAMPAIGNS MASS AND SOCIAL MEDIA CAMPAIGNS.OUR IN-COUNTRY TEAMS ALSO ASSISTED PARTNERSHIP FOR HEALTHY CITIES, FROM GIVING WORKSHOPS ON STRATEGIC COMMUNICATION IN BANGKOK, TO TECHNICAL ASSISTANCE ON CAMPAIGNS THAT ENCOURAGED AND ENFORCED LOCAL GOVERNMENT SMOKE-FREE INITIATIVES FROM AMMAN TO BENGALURU TO YANGON. OUR VITAL TEAM IN INDONESIA HAD A SOCIAL-MEDIA BREAKOUT MOMENT IN 2019. A POPULAR INDONESIAN FIGURE, PAK SUTOPO, KNOWN BECAUSE OF HIS WORK IN DISASTER RELIEF, AND A NON-SMOKER, DIED OF LUNG CANCER FROM WORKPLACE EXPOSURE TO SECONDHAND SMOKE. HIS VIDEO TESTIMONIAL ON VITAL'S ONGOING SOCIAL MEDIA CAMPAIGN IN INDONESIA GARNERED 3 MILLION VIEWS AND MEDIA COVERAGE IN THE JAKARTA POST, AMONG OTHER OUTLETS.2019 BRINGS 19 IMPRESSIVE WINS 2019 SAW VICTORIES IN SIX NEW SMOKE-FREE CITIES, INCLUDING THREE IN CHINA, IN QINHUANGDAO, A POPULAR TOURIST DESTINATION, WUHAN AND ZHANGJIAKOU; AS WELL AS ONE IN AMBON, AND ONE IN BOGOR, INDONESIA AND IN CHIAPAS, MEXICO. WE REALIZED FOUR E-CIGARETTE VICTORIES: IN INDIA WITH A BAN ON THE SALE, IMPORT AND MANUFACTURE OF THESE PRODUCTS; IN BRAZIL, WHERE WE RETAINED THE BAN DESPITE INDUSTRY PRESSURE TO LIFT IT; AND IN INDONESIA, WHERE WE ACHIEVED NATIONAL BAN ON INTERNET ADVERTISING. WE ALSO CELEBRATED AN EXTENDED SMOKE-FREE BAN IN SHENZHEN, CHINA (POPULATION: MORE THAN 12 MILLION) THAT NOW INCLUDES E-CIGARETTES. FIVE TOBACCO TAX WINS WERE ACHIEVED: TWO IN THE PHILIPPINES, AS WELL AS ONE EACH IN MEXICO, PAKISTAN AND TURKEY. A SUSTAINABLE MECHANISM IN BANGLADESH NOW ALLOWS FOR CAMPAIGNS TO RUN FREE OF COST ON GOVERNMENT CHANNELS. PICTORIAL WARNINGS WERE ADOPTED IN UZBEKISTAN, AND AFTER MANY DELAYS, A HARD-WON INCREASE IN PACK WARNING SIZE TO 60% WAS ACCOMPLISHED IN PAKISTAN. IN BRAZIL, WE FOUGHT BACK SUCCESSFULLY AGAINST FLAVORED CIGARETTES.

STREAM CLINICAL TRIAL:RESEARCH DIVISION WORKS TO GENERATE HIGH-QUALITY EVIDENCE TO GUIDE SIGNIFICANT PUBLIC HEALTH DECISIONS. THE STREAM CLINICAL TRIAL, TARGETED OPERATIONAL RESEARCH TRAINING, AND TECHNICAL ASSISTANCE TO NATIONAL TUBERCULOSIS PROGRAMS, ARE ALL PART OF THE USAID-FUNDED TREAT TB PROJECT. STREAM IS THE FIRST LARGE-SCALE, MULTI-COUNTRY CLINICAL TRIAL TO EXAMINE SHORTENED REGIMENS FOR MDR-TB. IN 2019, STAGE 1 OF STREAM, INITIATED BY THE UNION AND IMPLEMENTED JOINTLY WITH VITAL STRATEGIES AND PART-NERS, GENERATED IMPORTANT RESULTS THAT PLAYED A SIGNIFICANT ROLE IN WHO'S ENDORSEMENT OF A SHORTER STANDARDIZED 9- TO 11-MONTH REGIMEN FOR MDR-TB, WHICH REDUCES TREATMENT TIME AND CUTS THE OVERALL PILL BURDEN BY ABOUT 60%. THE FINAL RESULTS WERE PUBLISHED IN THE NEW ENGLAND JOURNAL OF MEDICINE IN EARLY 2019. STREAM STAGE 2 IS EVALUATING THE EFFICACY, SAFETY AND COST OF AN ALL-ORAL TREATMENT REGIMEN THAT CONTAINS ONE OF THE NEWEST ANTI-TB DRUGS, BEDAQUILINE. RECRUITMENT FOR STAGE 2 WAS COMPLETED IN JANUARY 2020, WITH 588 PARTICIPANTS RECRUITED, MAKING STREAM THE LARGEST RECRUITED TRIAL FOR MDR-TB.COMMUNITY ENGAGEMENT IS A VITAL PART OF STREAM AT ALL 13 TRIAL SITES, ENCOMPASSING A BROAD RANGE OF ACTIVITIES DESIGNED TO BRIDGE THE NEEDS OF AFFECTED COMMUNITIES AND RESEARCHERS. THE DIVISION'S WORK IS FUELING SUSTAINABLE CHANGE IN THE COUNTRIES WHERE IT WORKS, IN PARTICULAR BY BUILDING LOCAL CAPACITY TO DIAGNOSE, TREAT, AND CONDUCT RESEARCH ON MDR-TB AND FOR COMMUNITIES TO PARTICIPATE IN THE RESEARCH CYCLE. THE DIVISION HAS ALSO TRAINED HUNDREDS OF HEALTH CARE PROFESSIONALS IN ASIA, AFRICA, AND LATIN AMERICA TO CONDUCT OPERATIONAL RESEARCH INDEPENDENTLY, ENSURING THAT PROGRAM DATA ARE USED TO IMPROVE IMPLEMENTATION OF NATIONAL TB PROGRAMS

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