| SACRED HEART HEALTH SERVICES | $142,545,417 | $131,551,300 |
| MOUNT MARTY COLLEGE | $22,874,486 | $23,811,331 |
| LEWIS AND CLARK BEHAVIORAL | $10,886,127 | $10,128,327 |
| ABILITY BUILDING SERVICES INC | $6,101,184 | $6,064,412 |
| YANKTON AREA PROGRESSIVE GROWTH INC | $1,456,841 | $1,236,969 |
| NATIONAL FIELD ARCHERY ASSOCIATION FOUNDATION | $891,828 | $1,198,546 |
| NATIONAL FIELD ARCHERY ASSOCIATION | $1,104,133 | $1,082,719 |
| LEWIS AND CLARK HEALTH EDUCATION AND SERVICE AGENCY | $938,271 | $855,874 |
| UNITED WAY AND VOLUNTEER SERVICES OF GREATER YANKTON | $729,945 | $793,029 |
| YANKTON TRANSIT INC | $813,354 | $720,735 |
| YANKTON AREA CHAMBER OF COMMERCE | $636,125 | $644,440 |
| RIVER CITY DOMESTIC VIOLENCE CENTER | $461,772 | $529,528 |
| YANKTON RURAL AREA HEALTH EDUCATION CENTER | $316,928 | $480,488 |
| YANKTON COUNTY HISTORICAL SOCIETY | $596,314 | $469,137 |
| YANKTON AREA SENIOR CITIZEN | $449,864 | $453,583 |
| BENEDICTINE HEALTH FOUNDATION | $1,217,726 | $435,562 |
| HABITAT FOR HUMANITY OF YANKTON COUNTY | $378,325 | $426,202 |
| REGIONAL TECHNICAL EDUCATION CENTER INC | $285,083 | $329,850 |
| ALPHA XI DELTA BUILDING CORPORATION | $297,371 | $306,087 |
| HEARTLAND HUMANE SOCIETY INC | $277,119 | $295,114 |
| EDGAR W FREEMAN CHARITABLE TRUST | $602,830 | $284,411 |
| PATHWAYS SHELTER FOR THE HOMELESS | $418,051 | $281,984 |
| SOUTHEAST SOUTH DAKOTA TOURISM ASSOC | $285,495 | $276,888 |
| CONTACT-REFERRAL CENTER FOR HUMAN RESOURCES | $223,159 | $227,016 |
| SOUTHEAST SOUTH DAKOTA EXPERIM | $228,476 | $216,790 |