GAPPS GLOBAL ALLIANCE TO PREVENT PREMATURITY A
19009 33RD AVE W NO 200, LYNNWOOD, WA 98036 www.gapps.org

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Organizations Filed Purposes: GAPPS' MISSION IS TO IMPROVE BIRTH OUTCOMES WORLDWIDE.

EVERY PREEMIE- SCALE. EVERY PREEMIE IS A FIVE-YEAR, $9 MILLION UNITED STATES AGENCY FOR INTERNATIONAL DEVELOPMENT (USAID) COOPERATIVE AGREEMENT DESIGNED TO EXPAND DELIVERY OF EVIDENCE-BASED STRATEGIES, BUILDING ON EXISTING, INTEGRATED PLATFORMS IN MATERNAL, NEWBORN, CHILD AND ADOLESCENT HEALTH AND FAMILY PLANNING IN 23 USAID PRIORITY COUNTRIES IN AFRICA AND ASIA.EVERY PREEMIE IS A CONSORTIUM OF THE GLOBAL ALLIANCE TO PREVENT PREMATURITY AND STILLBIRTH (GAPPS), PROJECT CONCERN INTERNATIONAL (PCI), AND THE AMERICAN COLLEGE OF NURSE-MIDWIVES (ACNM). USAID, THROUGH ITS GLOBAL HEALTH OFFICE AND ITS COUNTRY MISSIONS, AS WELL AS NATIONAL MINISTRIES OF HEALTH, ARE KEY PARTNERS, AS ARE ORGANIZATIONS INCLUDING ACADEMIC INSTITUTIONS, NATIONAL PROGRAMS, AND NGOS AT THE COUNTRY LEVEL.GAPPS LEADS EVIDENCE AND KNOWLEDGE SHARING, PROGRAM LEARNING, AND IMPLEMENTATION RESEARCH ACTIVITIES; PCI LEADS COMMUNITY CAPACITY BUILDING AND MOBILIZATION ACTIVITIES; AND ACNM LEADS HEALTHCARE PROVIDER CAPACITY BUILDING AND PERFORMANCE IMPROVEMENT ACTIVITIES.

PREVENTING PRETERM BIRTH INITIATIVE. THE PREVENTING PRETERM BIRTH (PPB) INITIATIVE IS A $20 MILLION PROGRAM FUNDED BY THE BILL & MELINDA GATES FOUNDATION TO ACCELERATE RESEARCH BY FUNDING PROJECTS FOCUSED ON DISCOVERING AND DEVELOPING INTERVENTIONS TO PREVENT PRETERM BIRTH, WITH A FOCUS ON PREVENTION STRATEGIES APPLICABLE IN LOW RESOURCE SETTINGS, WHERE THE BURDEN OF PREMATURITY IS HIGH. RESEARCHERS CONDUCTING PROSPECTIVE STUDIES OF PREGNANT WOMEN IN LOW-INCOME COUNTRIES ARE CONNECTED WITH A CONSORTIUM OF INNOVATIVE RESEARCHERS INVESTIGATING THE CAUSES OF PRETERM BIRTH AND METHODS FOR PREVENTION. THE PPB INITIATIVE IS ORGANIZED AROUND THREE SETS OF PROJECTS, ALL WITH A COMMON GOAL OF UNDERSTANDING WHY PRETERM BIRTH HAPPENS AND HOW IT CAN BE PREVENTED:PPB 1 FOCUSES ON IMPLEMENTING A COMPREHENSIVE PREVENTION RESEARCH AGENDA THROUGH A CONSORTIUM OF PROJECTS THAT INVESTIGATE MECHANISMS LEADING TO PRETERM BIRTH AND NOVEL STRATEGIES FOR PREVENTION LINKED TO RIGOROUS PROSPECTIVE STUDIES OF PREGNANT WOMEN IN LOW-INCOME COUNTRIES.PPB 2 AIMS TO HARMONIZE CURRENT AND NEW GLOBAL BIOREPOSITORIES, AND DEVELOP FIELD SITES IN LOW RESOURCE SETTINGS WHERE COHORTS OF PREGNANT WOMEN CONTRIBUTE DATA AND BIOSPECIMENS TO A BIOREPOSITORY TO IMPROVE RESEARCHER ACCESS AND ACCELERATE DISCOVERY.PPB 3 SUPPORTS A COLLABORATIVE RESEARCH EFFORT USING A HIGH-THROUGHPUT SYSTEMS BIOLOGY APPROACH TO UNDERSTAND THE BIOLOGICAL MECHANISMS LEADING TO PRETERM BIRTH AND OTHER ADVERSE PREGNANCY OUTCOMES.THE PPB INITIATIVE HAS AWARDED 13 RESEARCH GRANTS THAT COLLECTIVELY FORM A GLOBAL CONSORTIUM BRIDGING INNOVATIVE BASIC SCIENCE INVESTIGATORS WITH STUDY SITES IN LOW-INCOME COUNTRIES.

BIOSERVICES. GAPPS BIOSERVICES WAS FOUNDED IN 2009 TO SERVE THE URGENT NEED FOR BIOLOGICAL SPECIMENS TO SUPPORT RESEARCH ON COMPLICATIONS IN PREGNANCY. GAPPS OFFERS FULL SERVICE BIOSPECIMEN MANAGEMENT INCLUDING BIOSPECIMEN PROCUREMENT AND MANAGEMENT, SAMPLE STORAGE AND TRACKING, AND MOLECULAR ANALYTE EXTRACTION. COMPREHENSIVE QUALITY CONTROL AND QUALITY ASSURANCE SYSTEMS ARE BUILT INTO EVERY COMPONENT OF OUR OPERATIONS. GAPPS HAS HARNESSED ITS EXPERTISE IN COLLECTION AND STORAGE OF A WIDE VARIETY OF SAMPLE TYPES AND THEIR DERIVATIVES TO PROVIDE INVESTIGATORS WITH HIGH QUALITY DATA AND BIOSPECIMENS TO SUPPORT TRANSLATIONAL RESEARCH AROUND THE WORLD, INCLUDING RESEARCH ON NORMAL AND ABNORMAL PREGNANCIES, HOW PREGNANCY AFFECTS MATERNAL AND CHILD HEALTH AFTER DELIVERY, AND FETAL ORIGINS OF DISEASES.GAPPS BIOSERVICES OPERATES A WIDELY-ACCESSIBLE BIOBANK OF STANDARDIZED, HIGH-QUALITY SPECIMENS LINKED TO DATA FROM DIVERSE POPULATIONS OF PREGNANT WOMEN AND THEIR BABIES. THE COLLECTION INCLUDES CONTRIBUTIONS FROM WOMEN REPRESENTING A RANGE OF RACIAL, ETHNIC, REGIONAL AND SOCIOECONOMIC BACKGROUNDS. IN THE UNITED STATES, GAPPS HAS RECRUITED AND FOLLOWED THE PREGNANCIES OF OVER 2,500 WOMEN, COLLECTING EXTENSIVE DEMOGRAPHIC AND MEDICAL DATA LINKED TO OVER 136,000 BANKED SPECIMENS. OVER 30,000 OF THESE HAVE BEEN DISTRIBUTED TO RESEARCHERS TO STUDY THE CAUSES OF PREGNANCY COMPLICATIONS, AND ULTIMATELY TO DEVELOP INTERVENTIONS TO SAVE THE LIVES OF MOTHERS AND BABIES.

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