| LIFE SCIENCES TRAINERS AND EDUCATORS NETWORK | $3,268,472 | $3,160,642 |
| WESTERN VIRGINIA FOUNDATION FOR THE ARTS AND SCIENCES | $2,083,244 | $3,117,380 |
| BLUE RIDGE PUBLIC TELEVISION INC | $2,285,558 | $3,073,744 |
| LOCAL OFFICE ON AGING | $3,947,242 | $2,908,218 |
| HABITAT FOR HUMANITY IN THE ROANOKE VALLEY | $3,127,145 | $2,883,308 |
| GIRL SCOUTS OF VIRGINIA SKYLINE COUNCIL INC | $2,529,044 | $2,721,577 |
| BLUE RIDGE BEHAVIORAL HEALTHCARE INC | $2,482,511 | $2,629,420 |
| ROANOKE VALLEY CONVENTION AND VISITORS BUREAU | $2,707,942 | $2,480,294 |
| RENEWANATION | $3,310,453 | $2,449,586 |
| ASSISI ANIMAL CLINICS OF VIRGINIA INC | $2,375,977 | $2,357,009 |
| JEFFERSON CENTER FOUNDATION LTD | $1,621,625 | $2,337,182 |
| VIRGINIA WESTERN COMMUNITY COLLEGE EDUCATIONAL FOUNDATION INC | $2,493,295 | $2,287,093 |
| CERTIFIED MEDICAL REPRESENTATIVES INSTITUTE INC | $3,082,044 | $2,247,811 |
| LABORERS DISTRICT COUNCIL OF VIRGINIA HEALTH AND WELFARE FUND | $1,770,935 | $2,214,362 |
| WESTERN VIRGINIA EMERGENCY MEDICAL SERVICES COUNCIL | $2,236,136 | $2,099,619 |
| KISSITO HEALTHCARE INC | $3,474,713 | $2,059,793 |
| ARCH ROANOKE | $2,099,211 | $2,029,051 |
| FAMILY SERVICE OF ROANOKE VALLEY | $2,082,914 | $1,873,819 |
| CARILION CLINIC FOUNDATION | $10,497,928 | $1,811,148 |
| SCOTT HILL INC | $1,703,692 | $1,694,482 |
| CHILD HEALTH INVESTMENT PARTNERSHIP | $1,735,135 | $1,656,910 |
| GOODWILL OF THE VALLEYS FOUNDATION INC | $140,546 | $1,553,357 |
| SHENANDOAH CLUB | $1,439,733 | $1,533,283 |
| COMMUNITY SCHOOL | $1,897,843 | $1,518,636 |
| TMA-ILA WELFARE PLAN | $1,525,706 | $1,429,251 |