| CARILION MEDICAL CENTER | $1,381,655,878 | $1,319,983,975 |
| DELTA DENTAL OF VIRGINIA | $730,806,957 | $711,628,850 |
| CARILION SERVICES INC | $267,707,517 | $265,476,443 |
| CARILION NEW RIVER VALLEY MEDICAL CENTER | $240,936,069 | $204,531,227 |
| AMITY FELLOWSERVE INC | $68,617,930 | $93,627,131 |
| GOODWILL INDUSTRIES OF THE VALLEY WORKS | $76,399,454 | $75,847,078 |
| HOLLINS UNIVERSITY CORPORATION | $55,719,065 | $55,954,890 |
| CARILION FRANKLIN MEMORIAL HOSPITAL | $48,613,274 | $46,770,114 |
| CARILION STONEWALL JACKSON HOSPITAL | $42,164,273 | $39,479,184 |
| LUTHERAN FAMILY SERVICES OF VIRGINIA INC | $34,898,994 | $35,414,522 |
| CARILION GILES COMMUNITY HOSPITAL | $34,729,921 | $34,839,900 |
| CARILION CLINIC | $37,323,120 | $28,723,516 |
| VIRGINIA LUTHERAN HOMES INC | $23,911,104 | $23,191,402 |
| FRIENDSHIP HEALTH AND REHAB CENTER INC | $22,395,332 | $22,816,322 |
| CORVESTA INC | $582,468 | $22,012,995 |
| DEPAUL COMMUNITY RESOURCES | $21,182,853 | $21,154,555 |
| TOTAL ACTION AGAINST POVERTY IN THE ROANOKE VALLEY | $21,000,650 | $20,781,058 |
| CARILION TAZEWELL COMMUNITY HOSPITAL | $14,878,705 | $18,128,738 |
| GOODWILL INDUSTRIES OF THE VALLEYS INC | $20,506,633 | $17,763,988 |
| FRIENDSHIP HEALTH AND REHAB CENTER SOUTH | $13,463,563 | $13,865,586 |
| OUR LADY OF HOPE HEALTH CENTER INC | $12,232,314 | $11,352,175 |
| NORTH CROSS SCHOOL | $17,982,358 | $11,023,646 |
| OUR LADY OF THE VALLEY INC | $12,049,490 | $10,163,621 |
| BLUE EAGLE CREDIT UNION | $10,128,635 | $9,691,996 |
| OUR LADY OF PEACE INC | $10,685,702 | $8,762,672 |